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53 Based on these findings, a randomised, double blind, placebo controlled phase 2 study was carried out in people with T2DM treated with lifestyle measures or metformin, aiming to assess the safety and efficacy of tirzepatide in comparison with placebo and dulaglutide 1.5 mg once weekly

Fortunately, we found that treatment with N-3 PUFAs and/or Vit D normalized caspase-3 and attenuated CaM-1 overexpression, as well as tau accumulation

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Glucose tolerance and insulin secretion have been investigated in patients with different thyroid status and experimental hypo- and hyperthyroid animal models, but not yielding a consistent explanation, which is likely due to the severity or duration of thyrotoxicosis or hormone treatment